2025 |
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Combining MicroED and native mass spectrometry for structural discovery of enzyme-biosynthetic inhibitor complexes
Niko W Vlahakis, Cameron W Flowers, Mengting Liu, Matthew Agdanowski, Samuel Johnson, Jacob A Summers, Catherine Keyser, Phoebe Russell, Samuel Rose, Julien Orlans, Nima Adhami, Yu Chen, Michael R Sawaya, Shibom Basu, Daniele De Sanctis, Soichi Wakatsuki, Hosea M Nelson, Joseph Loo, Yi Tang, View ORCID ProfileJose A Rodriguez BioRxiv 2025
Niko W Vlahakis, Cameron W Flowers, Mengting Liu, Matthew Agdanowski, Samuel Johnson, Jacob A Summers, Catherine Keyser, Phoebe Russell, Samuel Rose, Julien Orlans, Nima Adhami, Yu Chen, Michael R Sawaya, Shibom Basu, Daniele De Sanctis, Soichi Wakatsuki, Hosea M Nelson, Joseph Loo, Yi Tang, View ORCID ProfileJose A Rodriguez BioRxiv 2025
2024 |
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Fast event-based electron counting for small molecule structure determination by MicroED
Niko Vlahakis, Songrong Qu, Logan Richards, Lygia Silva deMoraes, Duilio Cascio, Hosea Nelson, Jose Rodriguez ChemRxiv 2024
Niko Vlahakis, Songrong Qu, Logan Richards, Lygia Silva deMoraes, Duilio Cascio, Hosea Nelson, Jose Rodriguez ChemRxiv 2024
Microcrystal electron diffraction-guided discovery of fungal metabolites
Delgadillo, D. A.; Wu, L.; Wang, C.; Zhang Y.; Burch, J. E.; Jha, K. K.; de Moraes, L. S.; Bills, G. F.; Tu, B. P.; Tang, Y.; Nelson, H. M. ChemRxiv 2024.
Delgadillo, D. A.; Wu, L.; Wang, C.; Zhang Y.; Burch, J. E.; Jha, K. K.; de Moraes, L. S.; Bills, G. F.; Tu, B. P.; Tang, Y.; Nelson, H. M. ChemRxiv 2024.
Assessing the Applicability of Bayesian Inference for Merging Small Molecule MicroED Data
Mai, H.; Peck, A.; Dalton, K. M.; de Moraes, L. S.; Burch, J. E.; Poitevin, F.; Nelson, H. M. ChemRxiv 2024.
Mai, H.; Peck, A.; Dalton, K. M.; de Moraes, L. S.; Burch, J. E.; Poitevin, F.; Nelson, H. M. ChemRxiv 2024.
Main Group-Catalyzed Cationic Claisen Rearrangements via Vinyl Carbocations
Williams, C. G.; Nistanaki, S. K.; Dong, K.; Lee, W.; Houk, K. N.; Nelson, H. M. Org. Lett. 2024, 26, 23, 4847–4852.
Williams, C. G.; Nistanaki, S. K.; Dong, K.; Lee, W.; Houk, K. N.; Nelson, H. M. Org. Lett. 2024, 26, 23, 4847–4852.
Distinct Function of Chlamydomonas CTRA-CTR Transporters in Cu Assimilation and Intracellular Mobilization
Strenkert, D.; Schmollinger, S.; Paruthiyil, S.; Brown, B. C.; Green, S.; Shafer, C. M.; Salomé, P.; Nelson, H.; Blaby-Haas, C. E.; Moseley, J. L.; Merchant, S. S. Metallomics 2024, 16, 3, mfae013.
Strenkert, D.; Schmollinger, S.; Paruthiyil, S.; Brown, B. C.; Green, S.; Shafer, C. M.; Salomé, P.; Nelson, H.; Blaby-Haas, C. E.; Moseley, J. L.; Merchant, S. S. Metallomics 2024, 16, 3, mfae013.
Structural Elucidation and Absolute Stereochemistry for Pharma Compounds Using MicroED
de Moraes, L. S.; Burch, J. E.; Delgadillo, D. A.; Hernandez Rodriguez, I.; Mai, H.; Smith, A. G.; Caille, S.; Walker, S. D.; Wurz, R. P.; Cee, V. J.; Rodriguez, J. A.; Gostovic, D.; Quasdorf, K.; Nelson, H. M. Org. Lett. 2024, in press.
de Moraes, L. S.; Burch, J. E.; Delgadillo, D. A.; Hernandez Rodriguez, I.; Mai, H.; Smith, A. G.; Caille, S.; Walker, S. D.; Wurz, R. P.; Cee, V. J.; Rodriguez, J. A.; Gostovic, D.; Quasdorf, K.; Nelson, H. M. Org. Lett. 2024, in press.
A Geometrically Flexible Three-Dimensional Nanocarbon
Tang, C.; Han, H.; Zhang, R.; de Moraes, L. S.; Qi, Y.; Wu, G.; Jones, C. G.; Hernandez Rodriguez, I.; Jiao, Y.; Liu, W.; Li, X.; Chen, H.; Bancroft, L.; Zhao, X.; Stern, C. L.; Guo, Q.; Krzyaniak, M. D.; Wasielewski, M. R.; Nelson, H. M.; Li, P.; Stoddart, J. F. J. Am. Chem. Soc. 2024, 146, 29, 20158–20167.
Tang, C.; Han, H.; Zhang, R.; de Moraes, L. S.; Qi, Y.; Wu, G.; Jones, C. G.; Hernandez Rodriguez, I.; Jiao, Y.; Liu, W.; Li, X.; Chen, H.; Bancroft, L.; Zhao, X.; Stern, C. L.; Guo, Q.; Krzyaniak, M. D.; Wasielewski, M. R.; Nelson, H. M.; Li, P.; Stoddart, J. F. J. Am. Chem. Soc. 2024, 146, 29, 20158–20167.
Gas-Induced Electrical and Magnetic Modulation of Two-Dimensional Conductive Metal-Organic Framework
Meng, Z.; Stolz, R. M.; de Moraes, L. S.; Jones, C. G.; Eagleton, A. M.; Nelson, H. M.; Mirica, K. A. Angew. Chem. Int. Ed. 2024, 63, 24, e202404290.
Meng, Z.; Stolz, R. M.; de Moraes, L. S.; Jones, C. G.; Eagleton, A. M.; Nelson, H. M.; Mirica, K. A. Angew. Chem. Int. Ed. 2024, 63, 24, e202404290.
A New Topological Class of Interlocked and Interwoven Nanocarbons via Dynamic C-C Bond Formation
Bergman, H. M.; Fan, A., Jones, C. G.; Rothenberger, A. J.; Jha, K. K.; Handford, R. C.; Nelson, H. M.; Liu, Y.; Tilley, T. D. ChemRxiv 2024.
Bergman, H. M.; Fan, A., Jones, C. G.; Rothenberger, A. J.; Jha, K. K.; Handford, R. C.; Nelson, H. M.; Liu, Y.; Tilley, T. D. ChemRxiv 2024.
Discovery and Characterization of Pyridoxal 5'-Phosphate-Dependent Cycloleucine Synthases
Abad, A. N.; Seshadri, K.; Ohashi, M.; Delgadillo, D. A.; de Moraes, L. S.; Nagasawa, K. K.; Liu, M.; Johnson, S.; Nelson, H. M.; Tang, Y. J. Am. Chem. Soc. 2024, 146, 21, 14672–14684.
Abad, A. N.; Seshadri, K.; Ohashi, M.; Delgadillo, D. A.; de Moraes, L. S.; Nagasawa, K. K.; Liu, M.; Johnson, S.; Nelson, H. M.; Tang, Y. J. Am. Chem. Soc. 2024, 146, 21, 14672–14684.
Accessing Medium-Sized Rings via Vinyl Carbocation Intermediates
Zhao, Z.; Popov, S.; Lee, W.; Burch, J. E.; Delgadillo, D. A.; Kim, L. J.; Shahgholi, M.; Lebrón-Acosta, N.; Houk, K. N.; Nelson, H. M. Org. Lett. 2024, 26, 5, 1000–1005.
Zhao, Z.; Popov, S.; Lee, W.; Burch, J. E.; Delgadillo, D. A.; Kim, L. J.; Shahgholi, M.; Lebrón-Acosta, N.; Houk, K. N.; Nelson, H. M. Org. Lett. 2024, 26, 5, 1000–1005.
High-throughput Identification of Crystalline Natural Products from Crude Extracts Enabled by Microarray Technology and MicroED
Delgadillo, D. A.; Burch, J. E.; Kim, L. J.; de Moraes L.; Niwa, K.; Williams, J.; Tang, M. J.; Lavallo, V.; Chhetri, B.; Jones, C. G.; Rodriguez, I. H.; Signore, J.; Marquez, L.; Bhanushali, R.; Greene, M.; Woo, S.; Kubanek, J.; Quave, C. L.; Tang, Y.; Nelson, H. M. ACS Cent. Sci. 2024, 10, 1, 176–183.
Delgadillo, D. A.; Burch, J. E.; Kim, L. J.; de Moraes L.; Niwa, K.; Williams, J.; Tang, M. J.; Lavallo, V.; Chhetri, B.; Jones, C. G.; Rodriguez, I. H.; Signore, J.; Marquez, L.; Bhanushali, R.; Greene, M.; Woo, S.; Kubanek, J.; Quave, C. L.; Tang, Y.; Nelson, H. M. ACS Cent. Sci. 2024, 10, 1, 176–183.
2023 |
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Genome Mining from Agriculturally Relevant Fungi Led to a D-Glucose Esterified Polyketide with a Terpene-like Core Structure
Yan, C.; Han, W.; Zhou, Q.; Niwa, K.; Tang, M. J.; Burch, J. E.; Zhang, Y.; Delgadillo, D. A.; Sun, Z.; Wu, Z.; Jacobsen, S. E.; Nelson, H. M.; Houk, K. N.; Tang, Y. J. Am. Chem. Soc. 2023, 145, 46, 25080–25085.
Yan, C.; Han, W.; Zhou, Q.; Niwa, K.; Tang, M. J.; Burch, J. E.; Zhang, Y.; Delgadillo, D. A.; Sun, Z.; Wu, Z.; Jacobsen, S. E.; Nelson, H. M.; Houk, K. N.; Tang, Y. J. Am. Chem. Soc. 2023, 145, 46, 25080–25085.
A Heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus fumigatus sartorypyrone biosynthetic pathway
Lin, S. Y.; Oakley, C. E.; Jenkinson, C. B.; Chiang, Y. M.; Lee, C. K.; Jones, C. G.; Seidler, P. M.; Nelson, H. M.; Todd, R. B.; Wang, C.C.; Oakley, B.R. Chem. Sci. 2023, 14, 11022–11032.
Lin, S. Y.; Oakley, C. E.; Jenkinson, C. B.; Chiang, Y. M.; Lee, C. K.; Jones, C. G.; Seidler, P. M.; Nelson, H. M.; Todd, R. B.; Wang, C.C.; Oakley, B.R. Chem. Sci. 2023, 14, 11022–11032.
Cryptic Chemical Variation in a Marine Red Alga as Revealed by Nontargeted Metabolomics
Chhetri, B. K.; Mojib, N.; Moore, S. G.; Delgadillo, D. A.; Burch, J. E.; Barrett, N. H.; Gaul, D. A.; Marquez, L.; Soapi, K.; Nelson, H. M.; Quave, C. L.; Kubanek, J. ACS Omega 2023, 8, 15, 13899–13910.
Chhetri, B. K.; Mojib, N.; Moore, S. G.; Delgadillo, D. A.; Burch, J. E.; Barrett, N. H.; Gaul, D. A.; Marquez, L.; Soapi, K.; Nelson, H. M.; Quave, C. L.; Kubanek, J. ACS Omega 2023, 8, 15, 13899–13910.
α-Vinylation of Ester Equivalents via Main Group Catalysis for the Construction of Quaternary Centers
Williams, C. G.; Nistanaki, S. K.; Wells, C. W.; Nelson, H. M. Org. Lett. 2023, 25, 20, 3591–3595.
Williams, C. G.; Nistanaki, S. K.; Wells, C. W.; Nelson, H. M. Org. Lett. 2023, 25, 20, 3591–3595.
Chemoenzymatic Synthesis of (+)-Xyloketal B
Romero, E. O.; Perkins, J. C.; Burch, J. E.; Delgadillo, D. A.; Nelson, H. M.; Narayan, A. R. H. Org. Lett. 2023, 25, 9, 1547–1552.
Romero, E. O.; Perkins, J. C.; Burch, J. E.; Delgadillo, D. A.; Nelson, H. M.; Narayan, A. R. H. Org. Lett. 2023, 25, 9, 1547–1552.
Computational Exploration of the Nature of Li+-Ureide Anion Catalysis on Formation of Highly Reactive Vinyl Carbocations and Subsequent C–C Bond Forming Reactions
Lee, W.; Nelson, H. M.; Houk, K. N. J. Org. Chem. 2023, 88, 6, 3403–3408.
Lee, W.; Nelson, H. M.; Houk, K. N. J. Org. Chem. 2023, 88, 6, 3403–3408.
2022 |
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Sterically Invariant Carborane-Based Ligands for the Morphological and Electronic Control of Metal–Organic Chalcogenolate Assemblies
Mills, H. A.; Jones, C. G.; Anderson, K. P.; Ready, A. D.; Djurovich, P. I.; Khan, S. I.; Hohman, N. J.; Nelson, H. M.; Spokoyny, A. M. Chem. Mat. 2022, 15, 6933–6943.
Mills, H. A.; Jones, C. G.; Anderson, K. P.; Ready, A. D.; Djurovich, P. I.; Khan, S. I.; Hohman, N. J.; Nelson, H. M.; Spokoyny, A. M. Chem. Mat. 2022, 15, 6933–6943.
Catalytic asymmetric C–H insertion reactions of vinyl carbocations
Nistanaki, S. K.; Williams, C. G.; Wigman, B.; Wong J. J.; Haas, B. C.; Popov, S.; Werth, J.; Sigman, M. S.; Houk, K. N.; Nelson, H. M. Science 2022, 378, 1085–1091.
This article was highlighted in Nature, C&EN, & The Caltech Weekly.
Nistanaki, S. K.; Williams, C. G.; Wigman, B.; Wong J. J.; Haas, B. C.; Popov, S.; Werth, J.; Sigman, M. S.; Houk, K. N.; Nelson, H. M. Science 2022, 378, 1085–1091.
This article was highlighted in Nature, C&EN, & The Caltech Weekly.
Cesium carbonate mediated C–H functionalization of perhalogenated 12-vertex carborane anions
Lovera, S. O; Bagsdasarian, A. L; Guo, J; Nelson, H. M.; Lavallo, V. Chem. Commun. 2022, 58, 4060–4062.
Lovera, S. O; Bagsdasarian, A. L; Guo, J; Nelson, H. M.; Lavallo, V. Chem. Commun. 2022, 58, 4060–4062.
Electrochemical Fluorination of Vinyl Boronates Through Donor-Stabilized Vinyl Carbocation Intermediates
Wigman, B.; Lee, W.; Wei, W.; Houk, K. N.; Nelson, H. M. Angew. Chem. Int. Ed. 2022, 60, e202113972.
First appeared on ChemRxiv.
Wigman, B.; Lee, W.; Wei, W.; Houk, K. N.; Nelson, H. M. Angew. Chem. Int. Ed. 2022, 60, e202113972.
First appeared on ChemRxiv.
Sterically Invariant Carborane-Based Ligands for the Morphological and Electronic Control of Metal–Organic Chalcogenolate Assemblies
Mills, H. A.; Jones, C. G.; Anderson, K. P.; Ready, A. D.; Djurovich, P. I.; Khan, S. I.; Hohman, N. J.; Nelson, H. M.; Spokoyny, A. M. Chem. Mat. 2022, 15, 6933–6943.
Mills, H. A.; Jones, C. G.; Anderson, K. P.; Ready, A. D.; Djurovich, P. I.; Khan, S. I.; Hohman, N. J.; Nelson, H. M.; Spokoyny, A. M. Chem. Mat. 2022, 15, 6933–6943.
2021 |
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Conductive Stimuli-Responsive Coordination Network Linked with Bismuth for Chemiresistive Gas Sensing
Aykanat, A.; Jones, C. G.; Cline, E.; Stolz, R. M.; Meng, Z.; Nelson, H. M.; Mirica, K. A. ACS Appl. Mater. Interfaces 2021, 50, 60306–60318.
Aykanat, A.; Jones, C. G.; Cline, E.; Stolz, R. M.; Meng, Z.; Nelson, H. M.; Mirica, K. A. ACS Appl. Mater. Interfaces 2021, 50, 60306–60318.
Solution-processable and functionalizable ultra-high molecular weight polymers via topochemical synthesis
Anderson, C. L.; Li, H.; Jones, C. G.; Teat, S. J.; Settineri, N. S.; Dailing, E. A.; Liang, J.; Mao, H.; Klivansky, L. M.; Li, X.; Reimer, J. A.; Nelson, H. M.; Liu, Y. Nat. Commun. 2021, 12, 1–8.
Anderson, C. L.; Li, H.; Jones, C. G.; Teat, S. J.; Settineri, N. S.; Dailing, E. A.; Liang, J.; Mao, H.; Klivansky, L. M.; Li, X.; Reimer, J. A.; Nelson, H. M.; Liu, Y. Nat. Commun. 2021, 12, 1–8.
Unraveling the Electrical and Magnetic Properties of Lawyered Conductive Metal− Organic Framework With Atomic Precision
Meng, Z.; Jones, C. G.; Farid, S.; Khan, I. U.; Nelson, H. M.; Mirica, K. A. Angew. Chem. Int. Ed. 2021, 60, 2–11.
Meng, Z.; Jones, C. G.; Farid, S.; Khan, I. U.; Nelson, H. M.; Mirica, K. A. Angew. Chem. Int. Ed. 2021, 60, 2–11.
Putting MicroED to the Test: An Account of the Evaluation of 30 Diverse Pharmaceutical Compounds
Burch, J. E.; Smith, A. G.; Caille, S.; Walker, S. D.; Wurz, R.; Cee, V. J.; Rodriguez, J.; Gostovic, D.; Quasdorf, K.; Nelson, H. M. ChemRxiv 2021.
Burch, J. E.; Smith, A. G.; Caille, S.; Walker, S. D.; Wurz, R.; Cee, V. J.; Rodriguez, J.; Gostovic, D.; Quasdorf, K.; Nelson, H. M. ChemRxiv 2021.
Biosynthesis of the Fusarium Mycotoxin (–)-Sambutoxin
Go, E. B.; Kim, L. J.; Nelson, H. M.; Ohashi, M.; Tang, Y. Org. Lett. 2021, 23, 7819–7823.
Go, E. B.; Kim, L. J.; Nelson, H. M.; Ohashi, M.; Tang, Y. Org. Lett. 2021, 23, 7819–7823.
Prospecting for natural products by genome mining and microcystal electron diffraction
Kim, L. J.; Ohashi, M.; Tan, D.; Asay, M.; Cascio, D.; Rodriguez, J; Tang, Y.; Nelson, H. M. Nat. Chem. Bio. 2021, 17, 872–877.
This article was highlighted in C&EN.
First appeared on ChemRxiv.
Kim, L. J.; Ohashi, M.; Tan, D.; Asay, M.; Cascio, D.; Rodriguez, J; Tang, Y.; Nelson, H. M. Nat. Chem. Bio. 2021, 17, 872–877.
This article was highlighted in C&EN.
First appeared on ChemRxiv.
Enhanced Gearing Fidelity Achieved Through Macrocyclization of a Solvated Molecular Spur Gear
Jellen, M. J.; Liepuoniute, I.; Jin, M.; Jones, C. G.; Yang, S.; Jiang, X.; Nelson, H. M.; Houk, K. N.; Garcia-Garibay, M. A. J. Am. Chem. Soc. 2021, 143, 7740–7747.
Jellen, M. J.; Liepuoniute, I.; Jin, M.; Jones, C. G.; Yang, S.; Jiang, X.; Nelson, H. M.; Houk, K. N.; Garcia-Garibay, M. A. J. Am. Chem. Soc. 2021, 143, 7740–7747.
Structural Revision of the Lomaiviticins
Kim, L. J.; Xue, M.; Li, X.; Xu, Z.; Paulson, E.; Mercado, B. Q.; Nelson, H. M.; Herzon, S. J. Am. Chem. Soc. 2021, 143, 6578–6585.
This article was highlighted in C&EN.
First appeared on ChemRxiv.
Kim, L. J.; Xue, M.; Li, X.; Xu, Z.; Paulson, E.; Mercado, B. Q.; Nelson, H. M.; Herzon, S. J. Am. Chem. Soc. 2021, 143, 6578–6585.
This article was highlighted in C&EN.
First appeared on ChemRxiv.
Isolation and X-ray Crystal Structure of an Electrogenerated TEMPO-N3 Charge-Transfer Complex
Nelson, H. M.; Siu, J. C.; Saha, A.; Cascio, D.; MacMillan, S. N.; Wu, S. B.; Lu, C.; Rodriguez, J. A.; Houk, K. N.; Lin, S. Org. Lett. 2021, 2, 454–458.
First appeared on ChemRxiv.
Nelson, H. M.; Siu, J. C.; Saha, A.; Cascio, D.; MacMillan, S. N.; Wu, S. B.; Lu, C.; Rodriguez, J. A.; Houk, K. N.; Lin, S. Org. Lett. 2021, 2, 454–458.
First appeared on ChemRxiv.
2020 |
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Elucidation of Diverse Solid-State Packing in a Family of Electron-Deficient Expanded Helicenes via Microcrystal Electron Diffraction (MicroED)
Samkian, A.; Kiel, G. R.; Jones, C. G.; Bergman, H.; Oktawiec, J.; Nelson, H. M.; Tilley, T. D. Angew. Chem. Int. Ed. 2020, 5, 2493–2499.
First appeared on ChemRxiv.
Samkian, A.; Kiel, G. R.; Jones, C. G.; Bergman, H.; Oktawiec, J.; Nelson, H. M.; Tilley, T. D. Angew. Chem. Int. Ed. 2020, 5, 2493–2499.
First appeared on ChemRxiv.
Chemocatalytic Amplification Probes Enable Transcriptionally-Regulated Au(I)-Catalysis in E. coli and Sensitive Detection of SARS-CoV-2 RNA Fragments
Green, S.; Wigman, B. W.; Nistanaki, S. K.; Montgomery, H.; Jones, C. G.; Nelson, H. M. ChemRxiv 2020.
Green, S.; Wigman, B. W.; Nistanaki, S. K.; Montgomery, H.; Jones, C. G.; Nelson, H. M. ChemRxiv 2020.
Terpene Tail-to-Head Polycyclization Mediated by Small Molecule Catalysts: A Weakly-Coordinating Anion Approach
Burch, J. E.; Bagdasarian, A. L.; Hooshmand, T.; Nelson, H. M. ChemRxiv 2020.
Burch, J. E.; Bagdasarian, A. L.; Hooshmand, T.; Nelson, H. M. ChemRxiv 2020.
Urea-Catalyzed Vinyl Carbocation Formation Enables Mild Functionalization of Unactivated C-H Bonds
Bagdasarian, A. L.; Popov, S.; Wigman, B.; Wei, W.; Lee, W.; Nelson, H. M. Org. Lett. 2020, 22, 7775–7779.
This article was highlighted in Synfacts.
First appeared on ChemRxiv.
Bagdasarian, A. L.; Popov, S.; Wigman, B.; Wei, W.; Lee, W.; Nelson, H. M. Org. Lett. 2020, 22, 7775–7779.
This article was highlighted in Synfacts.
First appeared on ChemRxiv.
Dewar Heterocycles as Versatile Monomers for Ring-Opening Metathesis Polymerization
Nistanaki, S. K.; Nelson, H. M. ACS Macro Lett. 2020, 9, 731–735.
First appeared on ChemRxiv.
Nistanaki, S. K.; Nelson, H. M. ACS Macro Lett. 2020, 9, 731–735.
First appeared on ChemRxiv.
Identification of Uric Acid Gluconucleoside–Ascaroside Conjugates in Caenorhabditis elegans by Combining Synthesis and MicroED
Curtis, B. J.; Kim, L. J.; Wrobel, C. J. J.; Eagen, J. M.; Smith, R. A.; Burch, J. E.; Le, H. H.; Artyukhin, A. B.; Nelson, H. M.; Schroeder, F. C. Org. Lett. 2020, 22, 6724–6728.
Curtis, B. J.; Kim, L. J.; Wrobel, C. J. J.; Eagen, J. M.; Smith, R. A.; Burch, J. E.; Le, H. H.; Artyukhin, A. B.; Nelson, H. M.; Schroeder, F. C. Org. Lett. 2020, 22, 6724–6728.
2019 |
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Vinyl Carbocations Generated under Basic Conditions and Their Intramolecular C–H Insertion Reactions
Wigman, B.; Popov, S.; Bagdasarian, A. L.; Shao, B.; Benton, T. R.; Williams, C. G.; Fisher, S. P.; Lavallo, V.; Houk, K. N.; Nelson, H. M. J. Am. Chem. Soc. 2019, 141, 9140–9144.
First appeared on ChemRxiv.
Wigman, B.; Popov, S.; Bagdasarian, A. L.; Shao, B.; Benton, T. R.; Williams, C. G.; Fisher, S. P.; Lavallo, V.; Houk, K. N.; Nelson, H. M. J. Am. Chem. Soc. 2019, 141, 9140–9144.
First appeared on ChemRxiv.
Regulating Transition Metal Catalysis Through Interference by Short RNAs
Green, S. A.; Montgomery, H. R.; Benton, T. R.; Chan, N. J.; Nelson, H. M. Angew. Chem. Int. Ed. 2019, 58,16400–16404.
First appeared on ChemRxiv.
Green, S. A.; Montgomery, H. R.; Benton, T. R.; Chan, N. J.; Nelson, H. M. Angew. Chem. Int. Ed. 2019, 58,16400–16404.
First appeared on ChemRxiv.
Nonclassical Applications of closo-Carborane Anions: From Main Group Chemistry and Catalysis to Energy Storage
Fisher, S. P.; Tomich, A. W.; Lovera, S. O.; Kleinsasser, J. F.; Guo, J.; Asay, M. J.; Nelson, H. M.; Lavallo, V. Chem. Rev. 2019, 119, 8262–8290.
Fisher, S. P.; Tomich, A. W.; Lovera, S. O.; Kleinsasser, J. F.; Guo, J.; Asay, M. J.; Nelson, H. M.; Lavallo, V. Chem. Rev. 2019, 119, 8262–8290.
A Concise Total Synthesis of (±)-Vibralactone
Nistanaki, S. K.; Boralsky, L. A.; Pan, R. D.; Nelson, H. M. Angew. Chem. Int. Ed. 2019, 58, 1724–1726.
First appeared on ChemRxiv.
Nistanaki, S. K.; Boralsky, L. A.; Pan, R. D.; Nelson, H. M. Angew. Chem. Int. Ed. 2019, 58, 1724–1726.
First appeared on ChemRxiv.
Characterization of Reactive Organometallic Species via MicroED
Jones, C. G.; Asay, M.; Kim, L. J.; Kleinsasser, J. F.; Saha, A.; Fulton, T. J.; Berkly, K. R.; Cascio, D.; Malyutin, A. G.; Conley, M. P.; Stoltz, B. M.; Lavallo, V.; Rodriguez, J. A.; Nelson, H. M. ACS Cent. Sci. 2019, 5, 1507–1513.
First appeared on ChemRxiv.
Jones, C. G.; Asay, M.; Kim, L. J.; Kleinsasser, J. F.; Saha, A.; Fulton, T. J.; Berkly, K. R.; Cascio, D.; Malyutin, A. G.; Conley, M. P.; Stoltz, B. M.; Lavallo, V.; Rodriguez, J. A.; Nelson, H. M. ACS Cent. Sci. 2019, 5, 1507–1513.
First appeared on ChemRxiv.
2018 |
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The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination
Jones, C. G.; Martynowycz, M. W.; Hattne, J.; Fulton, T. J.; Stoltz, B. M.; Rodriguez, J. A.; Nelson, H. M.; Gonen, T. ACS Cent. Sci. 2018, 4, 1587–1592.
First appeared on ChemRxiv.
This article was highlighted in ScienceNews, Science In the Pipeline, Nature & C&EN, NIH Director's Blog.
Jones, C. G.; Martynowycz, M. W.; Hattne, J.; Fulton, T. J.; Stoltz, B. M.; Rodriguez, J. A.; Nelson, H. M.; Gonen, T. ACS Cent. Sci. 2018, 4, 1587–1592.
First appeared on ChemRxiv.
This article was highlighted in ScienceNews, Science In the Pipeline, Nature & C&EN, NIH Director's Blog.
Teaching an old carbocation new tricks: Intermolecular C–H insertion reactions of vinyl cations
Popov, S.; Shao, B.; Bagdasarian, A. L.; Benton, T. R.; Zhou, L.; Yang, Z.; Houk, K. N.; Nelson, H. M. Science 2018, 361, 381-387.
This article was highlighted in Science, C&EN, & UCLA Newsroom.
Popov, S.; Shao, B.; Bagdasarian, A. L.; Benton, T. R.; Zhou, L.; Yang, Z.; Houk, K. N.; Nelson, H. M. Science 2018, 361, 381-387.
This article was highlighted in Science, C&EN, & UCLA Newsroom.
Arylation of hydrocarbons enabled by organosilicon reagents and weakly coordinating anions
Shao, B.*; Bagdasarian, A. L.*; Popov, S.; Nelson, H. M. Science 2017, 355, 1403–1407. (Asterisks indicate equal contribution.)
This article was highlighted in Synform.
Shao, B.*; Bagdasarian, A. L.*; Popov, S.; Nelson, H. M. Science 2017, 355, 1403–1407. (Asterisks indicate equal contribution.)
This article was highlighted in Synform.
